In this paper I examine two causal explanations for depression, the psychological and the biochemical. I argue for a holistic Jungian depth perspective that may, at times, allow for the wise use of antidepressant medications. I differentiate between pathological depression, where antidepressants may be therapeutically advisable, and transformative depression, where antidepressants may, at times, be helpful although in the long run their use is detrimental to in-depth healing.
I also explore the nature and therapeutic effectiveness of fluoxetine [Prozac], a potent and highly selective serotonin re-uptake blocker. According to medical literature it has proven itself to be effective in alleviating depression, while causing relatively few side effects.